News

AB-Therapeutics to participate at the annual meeting of the American Association of Cancer Research (AACR) in Chicago (USA)

During the congress the company will present the first data with the compound ABTL0812, on the mechanism of action and preclinical efficacy in experimental models of lung and pancreas.
The work presented has been selected by the evaluation committee of the AACR.

March 12, 2012

AB-Therapeutics, SL, pharmaceutical biotechnology company with a product in clinical phase planned for the third quarter of 2012, announced today that Jose Alfon, PhD, Director of Development, will participate in the Annual Meeting of the American Association of Cancer Research (AACR ) in Chicago from March 31 to April 4. Dr. Alfon will present the first data on the mechanism of action and preclinical efficacy in experimental models of lung and pancreas with the  compound ABTL0812. The work presented has been selected by the evaluation committee of the AACR.

ABTL0812 presents significant advantages over conventional chemotherapy: very low toxicity, oral administration, and most importantly, high efficacy. The product affects two cellular processes related to cell division and thus the proliferation of cancer cells: a) synthesis of DNA through inhibition of the expression of the dihydrofolate reductase (DHFR)
gene, and b) inhibiting mTOR pathway that is involved in protein synthesis. By blocking these two key cellular functions, tumor cells are killed by a mechanism called autophagy, in which cells digest themselves.

About AB-Therapeutics, SL

AB-
Therapeutics, SL is a research and development biopharmaceutical company founded in 2009 with headquarters in Bellaterra (Barcelona), Catalonia, Spain, located at the campus of the Autonomous University of Barcelona and with facilities planned in Boston in the US for 2012 .
AB-Therapeutics, SL aims to develop safer human therapies, based on the modulation of the activity of cell-membranes to treat various cancers, especially those with high medical needs due to its high mortality. The firm has a molecule, ABTL0812, in regulatory preclinical development, Phase I clinical trials (First in Man) is planned for the third quarter of 2012. A second drug candidate, ABTL1014 will begin preclinical development during the last quarter of 2012.
 

Contact:

Press:
Nuria Peláez
Tel +34 902 903 844
media.relations@ab-therapeutics.com
 
www.ab-therapeutics.com

Investors:
Carles Domenech, PhD
Tel +34 935 868 977
contact@ab-therapeutics.com
www.ab-therapeutics.com

LATEST NEWS

05.12.2018

News

AbilityPharma ha superado el millón de euros en la ronda de crowdfunding que abrió el pasado mes de septiembre + info
07.11.2018

News

Ability Pharmaceuticals Announces FDA-Orphan Drug Designation for ABTL0812 in Biliary Tract Cancer + info
19.09.2018

News

Ability Pharmaceuticals anuncia la inclusión del primer paciente en el estudio clínico de la fase 2 de ABTL0812 en Francia + info
24.08.2018

News

At AbilityPharma we are very pleased to announce the start of a crowdfunding campaign through de Capital Cell + info
19.02.2018

News

AbilityPharma Announces FDA Approval of Phase 1/2 Trial of ABTL0812 for Patients with Advanced Metastatic Pancreatic Cancer + info
13.12.2017

News

AbilityPharma Announces FDA Approval of IND for Phase 2 Trial of ABTL0812 in Patients with Endometrial Cancer or Squamous Non-Small Cell Lung Cancer + info
05.10.2017

News

Ability Pharmaceuticals announces the approval from the French Medicines Agency ANSM to initiate a Phase 1/2a Clinical Trial with ABTL0812 to treat patients with endometrial cancer or squamous lung cancer as first-line therapy in France + info
18.09.2017

News

Ability Pharmaceuticals Announces EMA-Orphan Drug Designation for ABTL0812 in Pancreatic Cancer + info
07.03.2017

News

Ability Pharma sponsors the 37th National Meeting of the Spanish Society of Pharmacology + info
© 2012 Ability Pharma / All Rights Reserved / Legal Notice / Privacy Police
NEORG